Santo Domingo is the commercial center of the Dominican Republic, where travelers will find themselves immersed in culture and tradition. It is a city lined with impressive modern architecture, interspersed with colonial design. It also provides access to some of the best beaches on the island. Discover more about this desirable vacation destination with the Santo Domingo Travel Guide. Rich with history, Santo Domingo is the oldest European settlement, and home to the first church, stronghold and street in the Americas. The Colonial Zone is a UNESCO World Heritage Site packed with 16th century Spanish Colonial buildings. The city has unbeatable weather, sunny and warm year-round with temperatures that reach an average of 86 °F.Retaining a truly authentic charm, the city is bustling with street vendors and daily markets where you can buy everything from fresh vegetables and flowers to handmade crafts. Santo Domingo has a thriving nightlife scene, with Latin dance clubs, cocktail bars and lounges, where there is never any shortage of entertainment. Those seeking a refuge from the bustle of the city can visit the Botanical Garden, or take a day-trip to some of the world’s most beautiful, serene beaches only a short drive away. It is a cultural wonderland where locals are proudly in touch with their heritage and the city is dotted with museums, theaters, galleries and many fantastic restaurants that serve up local cuisine. - Where is Santo Domingo?Santo Domingo is the capital of Dominican Republic and the oldest permanent city established by Europeans in the Western Hemisphere. It is situated on the southeast coast of the island of Hispaniola, astride the Ozama River which empties into the Caribbean Sea at the city’s harbor. - What is the best season for a vacation in Santo Domingo?Santo Domingo enjoys a nice, comfortable tropical climate year-round. The best time to visit is between December and March when there is less humidity and enjoyable temperatures averaging the mid-80s. If you are looking to experience some of the city's fantastic annual events and festivals, consider taking a trip sometime between April and July.